"The Pfizer-BioNTech COVID-19 Vaccine is an unapproved vaccine that may prevent COVID-19. " The Pfizer-BioNTech COVID-19 Vaccine is an unapproved vaccine. In clinical trials, approximately 23,000 individuals 12 years of age and older have received at least 1 dose of the Pfizer-BioNTech COVID-19 Vaccine. The duration of protection against COVID-19 is currently unknown. It is your choice to receive or not receive the Pfizer-BioNTech COVID-19 Vaccine Vaccine is still being studied in clinical trials.